An enhancer factor defect in a mutant Burkitt lymphoma cell line
نویسندگان
چکیده
RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 167 شماره
صفحات -
تاریخ انتشار 1988